EFEITOS DO TREINAMENTO RESISTIDO DURANTE O TRATAMENTO RADIOTERÁPICO EM MULHERES COM CÂNCER DE MAMA: UMA REVISÃO SISTEMÁTICA
uma revisão sistemática
DOI:
https://doi.org/10.37951/.2019v1i2.p30-46Palavras-chave:
Treinamento resistido, Exercício Físico, Radioterapia, Câncer de MamaResumo
Objetivo: Analisar os efeitos do treinamento resistido (TR) durante o tratamento radioterápico em mulheres com câncer de mama. Métodos: As buscas foram realizadas nas bases de dados: PubMed, Bireme, Web of Science e Scopus. Foram considerados todos os artigos publicados até fevereiro de 2019. Os critérios de inclusão foram: artigos em inglês, português e espanhol; durante tratamento radioterápico; e com desfechos relacionados ao desempenho muscular, composição corporal, parâmetros psicossociais e marcadores sanguíneos. Resultados: Foram incluídos três estudos. Esses três artigos envolveram a participação de 404 pacientes de câncer de mama recebendo o tratamento radioterápico, com a faixa etária média próxima aos 56 anos nesses estudos. Os três estudos obtiveram pontuação seis na avaliação de qualidade metodológica com a escala PEDro. Nos estudos foram verificados os efeitos do TR sobre os níveis de marcadores inflamatórios, desempenho de força muscular, fadiga, dor e qualidade de vida. Conclusão: O TR parece ser eficiente para ganhos de força muscular, redução dos níveis de fadiga e dor, e, promover a manutenção de marcadores inflamatórios durante o tratamento radioterápico.
Referências
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4. Reidunsdatter RJ, Rannestad T, Frengen J, Frykholm G. Early effects of contemporary breast radiation on health-related quality of life – Predictors of radiotherapy-related fatigue. Acta Oncol (Madr). 2011;50(0):1175–82.
5. Figueiredo FW dos S, Almeida TC do C, Cardial DT, Silva Maciel É da, Fonseca FLA, Adami F. The role of health policy in the burden of breast cancer in Brazil. BMC Womens Health. 2017;17(1):121.
6. Hwang JH, Chang HJ, Shim YH, Park WH, Park W, Huh SJ. Effects of Supervised Exercise Therapy in Patients Receiving Radiotherapy for Breast Cancer. Yonsei Med J. 2008;49(3):443–50.
7. Lipsett A, Barrett S, Haruna F, Mustian K, Donovan AO. The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life : A systematic review and meta-analysis. The Breast. 2017;32:144–55.
8. Battaglini CL, Mills RC, Phillips BL, Lee JT, Story CE, Nascimento MG, et al. Twenty-five years of research on the effects of exercise training in breast cancer survivors: A systematic review of the literature. World J Clin Oncol. 2014 May;5(2):177–90.
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11. Paoli A, Pacelli QF, Marcolin G, Guzzinati S, Neri M, Bianco A, et al. Effects of three distinct protocols of fitness training on body composition , strength and blood lactate. J Sport Med Phys Fit. 2010;50(1):43–51.
12. Bird SP, Tarpenning KM, Marino FE. Programmes to Enhance Muscular Fitness A Review of the Acute Programme Variables. Sport Med. 2005;35(10):841–51.
13. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.
14. Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M. Reliability of the PEDro Scale for Rating Quality of Randomized. 2003;83(8):713–21.
15. Schmidt ME, Meynköhn A, Habermann N, Wiskemann J, Oelmann J, Hof H, et al. Resistance Exercise and Inflammation in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy: Mediation Analysis From a Randomized, Controlled Intervention Trial. Int J Radiat Oncol [Internet]. 2016 Feb [cited 2018 Mar 20];94(2):329–37. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0360301615266552
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17. Wiskemann J, Schmidt ME, Klassen O, Debus J, Ulrich CM, Potthoff K, et al. Effects of 12-week resistance training during radiotherapy in breast cancer patients. Scand J Med Sci Sports. 2016;1(1):1–11.
18. Pierce BL, Ballard-barbash R, Bernstein L, Baumgartner RN, Neuhouser ML, Wener MH, et al. Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients. J Clin Oncol. 2009;27(21):3437–44.
19. Fauzee NSJ, Dong Z, Wang Y. Taxanes : Promising Anti-Cancer Drugs. Asian Pacific J Cancer Prev. 2011;12(0):837–51.
20. ICRU ICORUAM. International Commission on Radiation Units and Measurements. J ICRU. 2013;13(1):1–2.
21. van der Willik KD, Koppelmans V, Hauptmann M, Compter A, Ikram MA, Schagen SB. Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study. Breast Cancer Res. 2018 Nov;20(1):135.
22. Zahid H, Simpson ER, Brown KA. Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer. Curr Opin Pharmacol. 2016 Dec;31:90–6.
23. Simonavice E, Liu P-Y, Ilich JZ, Kim J-S, Arjmandi B, Panton LB. The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors. Appl Physiol Nutr Metab [Internet]. 2014 Jun [cited 2018 Mar 23];39(6):730–9. Available from: http://www.nrcresearchpress.com/doi/10.1139/apnm-2013-0281
24. Thompson CA, Thompson PA, Wright-Bea J, Nardi E, Frey GR. Metabolic Syndrome and Elevated C-Reactive Protein in Breast Cancer Survivors on Adjuvant Hormone Therapy. Jounal Women’s Heal. 2009;18(12):2041–7.
25. Katzung BG. Farmacologia Básica e Clínica. 12th ed. Porto Alegr: AMGH; 2014.
26. Battaglini C, Bottaro M, Dennehy C, Barfoot D, Shields E, Kirk D, et al. Efeitos do treinamento de resistência na força muscular e níveis de fadiga em pacientes com câncer de mama. Rev Bras Med Esporte. 2006;12(3):153–8.
27. Serra MC, Ryan AS, Ortmeyer HK, Addison O, Goldberg AP. Resistance training reduces inflammation and fatigue and improves physical function in older breast cancer survivors. Menopause. 2018 Feb;25(2):211–6.
28. Reis AD, Pereira PTVT, Diniz RR, de Castro Filha JGL, Dos Santos AM, Ramallo BT, et al. Effect of exercise on pain and functional capacity in breast cancer patients. Health Qual Life Outcomes. 2018 Apr;16(1):58.
29. Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvão DA, Pinto BM, et al. American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010;42(7):1409–26.
30. Barbalho MS., Gentil P, Fisher J, Steele J, Raiol RDA. There are no no-responders to low or high resistance training volumes among older women. Exp Gerontol. 2017;0(0):1–36.
31. Vieira CA, Battaglini CL, Vieira A, Vogt MFB, Oliveira RJ, Bottaro M. Effects of Rest Interval on Strength Recovery in Breast Cancer Survivors Effects of Rest Interval on Strength Recovery in Breast Cancer Survivors. Int Sport Med. 2015; ]
32. Gentil P, Bottaro M. Influence of Supervision Ratio on Muscle Adaptations to Resistance Training in Nontrained Subjects. J Strenght Cond Res. 2010;24(3):639–43.
2. WHO. Breast cancer: prevention and control. WORLD Heal Organ. 2015;
3. INCA C de ECG de AEIN de CJAG da S. ABC do câncer: abordagens básicas para o controle do câncer. 4th ed. Rio de Janeiro-RJ: Instituto Nacional de Câncer José Alencar Gomes da Silva; 2018.
4. Reidunsdatter RJ, Rannestad T, Frengen J, Frykholm G. Early effects of contemporary breast radiation on health-related quality of life – Predictors of radiotherapy-related fatigue. Acta Oncol (Madr). 2011;50(0):1175–82.
5. Figueiredo FW dos S, Almeida TC do C, Cardial DT, Silva Maciel É da, Fonseca FLA, Adami F. The role of health policy in the burden of breast cancer in Brazil. BMC Womens Health. 2017;17(1):121.
6. Hwang JH, Chang HJ, Shim YH, Park WH, Park W, Huh SJ. Effects of Supervised Exercise Therapy in Patients Receiving Radiotherapy for Breast Cancer. Yonsei Med J. 2008;49(3):443–50.
7. Lipsett A, Barrett S, Haruna F, Mustian K, Donovan AO. The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life : A systematic review and meta-analysis. The Breast. 2017;32:144–55.
8. Battaglini CL, Mills RC, Phillips BL, Lee JT, Story CE, Nascimento MG, et al. Twenty-five years of research on the effects of exercise training in breast cancer survivors: A systematic review of the literature. World J Clin Oncol. 2014 May;5(2):177–90.
9. Furmaniak AC, Menig M, Markes MH. Exercise for women receiving adjuvant therapy for breast cancer. Cochrane database Syst Rev [Internet]. 2016 Sep 21 [cited 2018 Mar 16];9:CD005001. Available from:ttp://doi.wiley.com/10.1002/14651858.CD005001.pub3
10. Santos WDN dos, Gentil P, Moraes RF de, Ferreira Júnior JB, Campos MH, de Lira CAB, et al. Chronic Effects of Resistance Training in Breast Cancer Survivors. Biomed Res Int [Internet]. 2017 [cited 2018 Mar 23];2017:1–18. Available from: https://www.hindawi.com/journals/bmri/2017/8367803/
11. Paoli A, Pacelli QF, Marcolin G, Guzzinati S, Neri M, Bianco A, et al. Effects of three distinct protocols of fitness training on body composition , strength and blood lactate. J Sport Med Phys Fit. 2010;50(1):43–51.
12. Bird SP, Tarpenning KM, Marino FE. Programmes to Enhance Muscular Fitness A Review of the Acute Programme Variables. Sport Med. 2005;35(10):841–51.
13. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.
14. Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M. Reliability of the PEDro Scale for Rating Quality of Randomized. 2003;83(8):713–21.
15. Schmidt ME, Meynköhn A, Habermann N, Wiskemann J, Oelmann J, Hof H, et al. Resistance Exercise and Inflammation in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy: Mediation Analysis From a Randomized, Controlled Intervention Trial. Int J Radiat Oncol [Internet]. 2016 Feb [cited 2018 Mar 20];94(2):329–37. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0360301615266552
16. Steindorf K, Schmidt ME, Klassen O, Oelmann J, Hof H, Debus J, et al. Progressive Resistance Training in Breast Cancer Patients Undergoing Adjuvant Radiotherapy: Results of a Randomized Trial. Med Sci Sports Exerc. 2014;46(5, 1):368–9.
17. Wiskemann J, Schmidt ME, Klassen O, Debus J, Ulrich CM, Potthoff K, et al. Effects of 12-week resistance training during radiotherapy in breast cancer patients. Scand J Med Sci Sports. 2016;1(1):1–11.
18. Pierce BL, Ballard-barbash R, Bernstein L, Baumgartner RN, Neuhouser ML, Wener MH, et al. Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients. J Clin Oncol. 2009;27(21):3437–44.
19. Fauzee NSJ, Dong Z, Wang Y. Taxanes : Promising Anti-Cancer Drugs. Asian Pacific J Cancer Prev. 2011;12(0):837–51.
20. ICRU ICORUAM. International Commission on Radiation Units and Measurements. J ICRU. 2013;13(1):1–2.
21. van der Willik KD, Koppelmans V, Hauptmann M, Compter A, Ikram MA, Schagen SB. Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study. Breast Cancer Res. 2018 Nov;20(1):135.
22. Zahid H, Simpson ER, Brown KA. Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer. Curr Opin Pharmacol. 2016 Dec;31:90–6.
23. Simonavice E, Liu P-Y, Ilich JZ, Kim J-S, Arjmandi B, Panton LB. The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors. Appl Physiol Nutr Metab [Internet]. 2014 Jun [cited 2018 Mar 23];39(6):730–9. Available from: http://www.nrcresearchpress.com/doi/10.1139/apnm-2013-0281
24. Thompson CA, Thompson PA, Wright-Bea J, Nardi E, Frey GR. Metabolic Syndrome and Elevated C-Reactive Protein in Breast Cancer Survivors on Adjuvant Hormone Therapy. Jounal Women’s Heal. 2009;18(12):2041–7.
25. Katzung BG. Farmacologia Básica e Clínica. 12th ed. Porto Alegr: AMGH; 2014.
26. Battaglini C, Bottaro M, Dennehy C, Barfoot D, Shields E, Kirk D, et al. Efeitos do treinamento de resistência na força muscular e níveis de fadiga em pacientes com câncer de mama. Rev Bras Med Esporte. 2006;12(3):153–8.
27. Serra MC, Ryan AS, Ortmeyer HK, Addison O, Goldberg AP. Resistance training reduces inflammation and fatigue and improves physical function in older breast cancer survivors. Menopause. 2018 Feb;25(2):211–6.
28. Reis AD, Pereira PTVT, Diniz RR, de Castro Filha JGL, Dos Santos AM, Ramallo BT, et al. Effect of exercise on pain and functional capacity in breast cancer patients. Health Qual Life Outcomes. 2018 Apr;16(1):58.
29. Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvão DA, Pinto BM, et al. American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010;42(7):1409–26.
30. Barbalho MS., Gentil P, Fisher J, Steele J, Raiol RDA. There are no no-responders to low or high resistance training volumes among older women. Exp Gerontol. 2017;0(0):1–36.
31. Vieira CA, Battaglini CL, Vieira A, Vogt MFB, Oliveira RJ, Bottaro M. Effects of Rest Interval on Strength Recovery in Breast Cancer Survivors Effects of Rest Interval on Strength Recovery in Breast Cancer Survivors. Int Sport Med. 2015; ]
32. Gentil P, Bottaro M. Influence of Supervision Ratio on Muscle Adaptations to Resistance Training in Nontrained Subjects. J Strenght Cond Res. 2010;24(3):639–43.
